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Two main types of lymphoma have been described to date, namely Hodgkin's and non-Hodgkin's lymphomas. Hodgkin's lymphomas rarely disseminate to the extralymphatic organs; by contrast, non-Hodgkin's lymphomas (NHLs) often invade extralymphatic organs (1).
 

1. Behrns KE, Sarr MG and Strickler JG: Pancreatic lymphoma: Is it a surgical disease? Pancreas. 9:662–667. 1994. View Article : Google Scholar : PubMed/NCBI





What are the Symptoms of Pancreatic Lymphoma?

Signs and symptoms of PPL are generally non-specific, meaning they could indicate many things in addition to PPL. A person could experience abdominal pain of variable severity and small bowel obstruction, along with the constellation of B symptoms, including loss of appetite, unexplained weight loss, fatigue, and night sweats.

Furthermore, patients with pancreatic lymphoma tend to have normal white blood cell counts. A trademark of the disease from the laboratory perspective is elevated LDH.

What is the Treatment and Prognosis for Pancreatic Lymphoma?

Treatment for PPL can include surgery (surgical resection), combination chemotherapy, or sometimes radiation along with chemotherapy. Studies suggest that when treated with chemotherapy, prognosis for PPL is very good.

SourcesPeisman M et al. A Case of Pancreatic Lymphoma Medscape General Medicine. 2007;9(3):32Kav T et al. Primary Pancreatic Lymphoma or Secondary Involvement: What Is the Difference? JOP. J Pancreas (Online) 2010 Sep 6; 11(5):482-483.Nayer H et al. Primary pancreatic lymphomas: a cytopathologic analysis of a rare malignancy Cancer. 2004; 102(5):315-21
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